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Question: 1 / 400

At what dosage does dopamine act as a Beta-1 agonist?

1-2 mcg/kg/min

2-10 mcg/kg/min

Dopamine functions differently depending on the dosage administered. At lower doses, specifically between 1 and 2 mcg/kg/min, dopamine primarily acts on dopaminergic receptors, leading to renal vasodilation. As the dosage increases to the range of 2 to 10 mcg/kg/min, dopamine predominantly stimulates beta-1 adrenergic receptors. This activation enhances cardiac contractility and heart rate, making this dosage range significant for patients who may be experiencing cardiac compromise or heart failure.

In summary, the dosage range of 2-10 mcg/kg/min is where dopamine acts as a beta-1 agonist, facilitating improved cardiac function in appropriate clinical scenarios. Higher dosages beyond this range would not primarily act on beta-1 receptors and may lead to additional effects, such as vasoconstriction via alpha-adrenergic receptor activation.

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10-20 mcg/kg/min

20-30 mcg/kg/min

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